The Anti-Phospho-BRD4 (S492, S494) Antibody (CABP1178) is a polyclonal antibody designed for research involving BRD4, a protein that plays a key role in regulating gene expression and cell growth. This antibody, raised in rabbits, is highly reactive with human samples and is validated for use in various applications including immunofluorescence and immunoprecipitation.BRD4 is a member of the bromodomain and extraterminal (BET) protein family and is known to interact with acetylated histones to regulate transcription. Phosphorylation of BRD4 at serine residues 492 and 494 has been implicated in the control of gene expression and the progression of various diseases, including cancer.
Research into the phosphorylation of BRD4 at these specific sites is essential for understanding the mechanisms underlying gene regulation and disease pathology. The Anti-Phospho-BRD4 (S492, S494) Antibody (CABP1178) enables the detection and analysis of phosphorylated BRD4 in cell cultures and tissue samples, making it a valuable tool for studies in cancer research and drug development.
