The Anti-Phospho-ALT-RPL36 (S142) Antibody (CABP1212) is a valuable tool for researchers studying the phosphorylation of the ALT-RPL36 protein at serine 142. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the phosphorylated form of ALT-RPL36, researchers can detect and analyze its presence in various cell types, providing insights into its functional role in cellular processes.ALT-RPL36, a ribosomal protein, plays a crucial role in protein synthesis and cellular growth. Phosphorylation of ALT-RPL36 at serine 142 may regulate its activity and impact key cellular functions.
Research into the phosphorylation status of ALT-RPL36 can provide valuable insights into its role in cellular signaling pathways, making this antibody essential for studies in molecular biology and cancer research.Understanding the phosphorylation status of ALT-RPL36 at serine 142 is important for unraveling its function in various cellular processes and disease states. This antibody offers a reliable and specific tool for investigating the role of this phosphorylation event in cellular signaling pathways, making it a valuable asset for researchers exploring the intricacies of protein regulation and cellular function.
Product Name:
Phospho-alt-RPL36-S142 Rabbit Polyclonal Antibody
SKU:
CABP1212
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic phosphorylated peptide around S142 of alt-RPL36.
Sequence:
SPSP A
Tested Applications:
WBELISADB
Recommended Dilution:
DB,1:500 - 1:1000 WB,1:500 - 1:2000
Conjugate:
Unconjugated
Observed MW:
Refer to figures
Alt-RPL36 is a protein co-encoded with human RPL36. Alt-RPL36 partially localizes to the endoplasmic reticulum, where it interacts with TMEM24, which transports the phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) precursor phosphatidylinositol from the endoplasmic reticulum to the plasma membrane. Alt-RPL36 contains four phosphoserine residues, point mutations of which abolish interaction with TMEM24 and, consequently, alt-RPL36 effects on PI3K signaling and cell size.
Purification Method:
Affinity purification
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Dot-blot analysis of all sorts of peptides using Phospho-alt-RPL36-S142 antibody (CABP1212) at 1:1000 dilution.Exposure time: 1s.
