The PGD Polyclonal Antibody (CAB0563) is ideal for researchers studying PGD, an enzyme involved in the prostaglandin biosynthesis pathway. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the PGD protein, this antibody allows for the detection and analysis of PGD expression in various cell types.PGD, also known as prostaglandin D2 synthase, plays a key role in the production of prostaglandins, lipid compounds that function as signaling molecules in inflammation and immune responses.
Given its involvement in these processes, PGD is a potential target for research in areas such as immunology and inflammatory diseases. Understanding the function and regulation of PGD can provide valuable insights into the development of therapies targeting the prostaglandin biosynthesis pathway.
Product Name:
PGD Rabbit Monoclonal Antibody
SKU:
CAB0563
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 384-483 of human PGD (P52209).
Sequence:
PELQ NLLL DDFF KSAV ENCQ DSWR RAVS TGVQ AGIP MPCF TTAL SFYD GYRH EMLP ASLI QAQR DYFG AHTY ELLA KPGQ FIHT NWTG HGGT VSSS SYNA
Tested Applications:
WBIF/ICCIPELISA
Recommended Dilution:
WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
5226
Clone Number:
ARC2516
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using PGD Rabbit mAb (CAB0563) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
