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PGC1 beta Rabbit Monoclonal Antibody (CAB4331)

SKU:
CAB4331
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
ERRL1
PERC
PGC-1(beta)
PGC1B
Research Area:
Epigenetics and Nuclear Signaling
$167 - $503
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:PGC1 beta Rabbit Monoclonal Antibody
SKU:CAB4331
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 924-1023 of human PGC1 beta (NP_573570.3).
Sequence:VFGE IEEC EVLT RNRR GEKY GFIT YRCS EHAA LSLT KGAA LRKR NEPS FQLS YGGL RHFC WPRY TDYD SNSE EALP ASGK SKYE AMDF DSLL KEAQ QSLH
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:PERC; ERRL1; PGC1B; PGC-1(beta); PGC1 beta
Positive Sample:HeLa,SH-SY5Y,Rat testis
Conjugate:Unconjugated
Cellular Localization:cytosol, mitochondrion, nucleoplasm, nucleus
Calculated MW:113kDa
Observed MW:113kDa

The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:133522
Clone Number:ARC2136
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using PGC1 beta Rabbit mAb (CAB4331) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.

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