The Anti-PGC1 beta Antibody (CAB4331) offered by AssayGenie is a valuable tool for researchers studying PGC1 beta, a key regulator of mitochondrial biogenesis and metabolism. This antibody, raised against PGC1 beta, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the PGC1 beta protein, researchers can gain insights into its role in cellular energy metabolism and mitochondrial function, making it essential for studies in metabolic diseases, aging, and exercise physiology.
Understanding the function of PGC1 beta is crucial for developing strategies to target mitochondrial dysfunction and metabolic disorders.
Product Name:
PGC1 beta Rabbit Monoclonal Antibody
SKU:
CAB4331
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 924-1023 of human PGC1 beta (NP_573570.3).
The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
133522
Clone Number:
ARC2136
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PGC1 beta Rabbit mAb (CAB4331) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
