The Anti-PFDN5 Antibody (CAB4101) is a valuable tool for researchers studying PFDN5, a protein involved in protein folding and chaperone activity. This polyclonal antibody, developed in rabbits, exhibits strong reactivity with human samples and is validated for use in Western blot applications. By binding to the PFDN5 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an indispensable asset for investigations in molecular biology and cellular physiology.PFDN5, also known as prefoldin subunit 5, plays a crucial role in protein folding processes, assisting in the maintenance of protein structure and function.
Its involvement in chaperone activity makes it a key player in cellular health and homeostasis. Research on PFDN5 is essential for advancing our understanding of protein folding mechanisms and their implications in diseases such as neurodegenerative disorders and cancer.The Anti-PFDN5 Antibody (CAB4101) offers researchers a reliable tool to explore the functions and mechanisms of PFDN5, paving the way for new insights and potential therapeutic strategies in protein folding-related pathologies.
Product Name:
PFDN5 Rabbit Monoclonal Antibody
SKU:
CAB4101
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-154 of human PFDN5 (Q99471).
Sequence:
LNVL NKSN EGKE LLVP LTSS MYVP GKLH DVEH VLID VGTG YYVE KTAE DAKD FFKR KIDF LTKQ MEKI QPAL QEKH AMKQ AVME MMSQ KIQQ LTAL GAAQ ATAK A
This gene encodes a member of the prefoldin alpha subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. The encoded protein may also repress the transcriptional activity of the proto-oncogene c-Myc. Alternatively spliced transcript variants encoding different isoforms have been described.
Purification Method:
Affinity purification
Gene ID:
5204
Clone Number:
ARC2111
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using PFDN5 Rabbit mAb (CAB4101) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
