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PER3 Rabbit Monoclonal Antibody (CAB2219)

SKU:
CAB2219
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
FASPS3
GIG13
$167 - $503
Frequently bought together:

Description

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Product Name:PER3 Rabbit Monoclonal Antibody
SKU:CAB2219
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 10-100 of human PER3 (P56645).
Sequence:GRRG AKDE ALGE ESGE RWSP EFHL QRKL ADSS HSEQ QDRN RVSE ELIM VVQE MKKY FPSE RRNK PSTL DALN YALR CVHS VQAN SEFF QIL
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:GIG13; FASPS3; PER3
Positive Sample:HeLa, Mouse lung, Mouse kidney, Rat lung
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Nucleus
Calculated MW:132kDa
Observed MW:132kDa

This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been linked to sleep disorders. Multiple transcript variants encoding different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:8863
Clone Number:ARC1893
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using PER3 Rabbit mAb (CAB2219) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.

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