PDZK1 Rabbit Monoclonal Antibody (CAB8874)
- SKU:
- CAB8874
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CAP70
- CLAMP
- NHERF-3
- NHERF3
- PDZD1
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PDZK1 Rabbit Monoclonal Antibody |
SKU: | CAB8874 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 420-519 of human PDZK1 (Q5T2W1). |
Sequence: | EDVI IEVN GVNV LDEP YEKV VDRI QSSG KNVT LLVC GKKA YDYF QAKK IPIV SSLA DPLD TPPD SKEG IVVE SNHD SHMA KERA HSTA SHSS SNSE DTEM |
Tested Applications: | IF/ICC ELISA |
Recommended Dilution: | IF/ICC,1:50 - 1:200 |
Synonyms: | CAP70; CLAMP; PDZD1; NHERF3; NHERF-3; PDZK1 |
Positive Sample: | HepG2 |
Conjugate: | Unconjugated |
Cellular Localization: | apical plasma membrane, extracellular exosome, microvillus membrane, plasma membrane |
Calculated MW: | 57kDa |
Observed MW: | 70kDa |
This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method: | Affinity purification |
Gene ID: | 5174 |
Clone Number: | ARC1334 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |