The PDLIM4 Polyclonal Antibody (CAB20463) is a valuable tool for researchers studying PDLIM4, a protein involved in cellular processes such as cytoskeletal organization and signal transduction. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot experiments. By specifically binding to the PDLIM4 protein, this antibody facilitates the detection and analysis of PDLIM4 in various cell types, making it ideal for investigations in cell biology and cancer research.PDLIM4, also known as the PDZ and LIM domain protein 4, plays a crucial role in regulating cell growth, differentiation, and migration.
Its involvement in these processes underscores its importance in various biological functions, including development and disease progression. Research into PDLIM4 can provide valuable insights into how disruptions in its function contribute to diseases such as cancer and neurological disorders. By understanding the role of PDLIM4, researchers can identify potential therapeutic targets for intervention in these conditions.
Product Name:
PDLIM4 Rabbit Polyclonal Antibody
SKU:
CAB20463
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 80-210 of human PDLIM4 (NP_003678.2).
cytoplasm, cytoskeleton, dendritic spine, early endosome lumen, nucleus, perinuclear region of cytoplasm, postsynaptic membrane, recycling endosome lumen, Z disc
Calculated MW:
35kDa
Observed MW:
35kDa
Enables alpha-actinin binding activity; protein homodimerization activity; and protein phosphatase binding activity. Involved in actin cytoskeleton reorganization. Located in several cellular components, including lamellipodium; perinuclear region of cytoplasm; and stress fiber. Part of filamentous actin. Implicated in osteoporosis.
Purification Method:
Affinity purification
Gene ID:
8572
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PDLIM4 antibody (CAB20463) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
