null

Anti-PDE2A Antibody (CAB20320)

SKU:
CAB20320
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
PDE2A1
PED2A4
cGSPDE
CGS-PDE
€359
Frequently bought together:

Description

Product Name:PDE2A Rabbit pAb
Product Code:CAB20320
Size:50uL, 100uL
Synonyms:PDE2A1, PED2A4, cGSPDE, CGS-PDE
Applications:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 400-500 of human PDE2A (NP_001230713.1).
Applications:WB
Recommended Dilutions:WB 1:500 - 1:2000
Reactivity:Human
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 400-500 of human PDE2A (NP_001230713.1).
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:5138
Uniprot:O00408
Calculated MW:105kDa
Observed MW:Refer to figures
UniProt Protein Function:PDE2A: Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Belongs to the cyclic nucleotide phosphodiesterase family. PDE2 subfamily. 4 isoforms of the human protein are produced by alternative splicing. Protein type: Phosphodiesterase; Nucleotide Metabolism - purine; EC 3.1.4.17; Mitochondrial Chromosomal Location of Human Ortholog: 11q13.4 Cellular Component: cytoplasm; cytosol; endoplasmic reticulum; Golgi apparatus; mitochondrial matrix; nucleus; perinuclear region of cytoplasm; plasma membrane; presynaptic membrane Molecular Function: 3',5'-cyclic-AMP phosphodiesterase activity; 3',5'-cyclic-GMP phosphodiesterase activity; calcium channel activity; cAMP binding; cGMP binding; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity; cyclic-nucleotide phosphodiesterase activity; drug binding; protein binding; protein homodimerization activity; TPR domain binding Biological Process: cAMP catabolic process; cAMP-mediated signaling; cGMP catabolic process; cGMP-mediated signaling; metabolic process; negative regulation of cAMP biosynthetic process; negative regulation of protein import into nucleus, translocation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of vascular permeability; positive regulation of inflammatory response; positive regulation of vascular permeability; protein targeting to mitochondrion
UniProt Protein Details:
NCBI Summary:
UniProt Code:O00408
NCBI GenInfo Identifier:3182954
NCBI Gene ID:5138
NCBI Accession:O00408.1
UniProt Secondary Accession:O00408,Q5J791, Q5J792, Q5J793, Q6ZMR1, B2R646, B3KRV5 E9PGI1, F6W5Z0
UniProt Related Accession:O00408
Molecular Weight:87,235 Da
NCBI Full Name:cGMP-dependent 3',5'-cyclic phosphodiesterase
NCBI Synonym Full Names:phosphodiesterase 2A
NCBI Official Symbol:PDE2A  
NCBI Official Synonym Symbols:PDE2A1; PED2A4; cGSPDE; CGS-PDE  
NCBI Protein Information:cGMP-dependent 3',5'-cyclic phosphodiesterase
UniProt Protein Name:cGMP-dependent 3',5'-cyclic phosphodiesterase
UniProt Synonym Protein Names:Cyclic GMP-stimulated phosphodiesterase; CGS-PDE; cGSPDE
Protein Family:cGMP-dependent 3',5'-cyclic phosphodiesterase
UniProt Gene Name:PDE2A  
UniProt Entry Name:PDE2A_HUMAN

Related Products