PCNT Rabbit Polyclonal Antibody (CAB20161)
- SKU:
- CAB20161
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- KEN
- PCN
- MOPD2
- PCNT2
- PCNTB
- PCTN2
- SCKL4
Frequently bought together:
Description
Product Name: | PCNT Rabbit Polyclonal Antibody |
SKU: | CAB20161 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 95-212 of human PCNT (NP_006022.3). |
Sequence: | GEKR EDLE QLQQ KQVN DHPP EQCG MFTV SDHP PEQH GMFT VGDH PPEQ RGMF TVSD HPPE QHGM FTVS DHPP EQRG MFTI SDHQ PEQR GMFT VSDH TPEQ RGIF TISD HPAE QRGM FT |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | KEN; PCN; MOPD2; PCNT2; PCNTB; PCTN2; SCKL4; PCNT |
Positive Sample: | SH-SY5Y,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | centriole, centrosome, cytosol |
Calculated MW: | 378kDa |
Observed MW: | 251kDa/378kDa |
The protein encoded by this gene binds to calmodulin and is expressed in the centrosome. It is an integral component of the pericentriolar material (PCM). The protein contains a series of coiled-coil domains and a highly conserved PCM targeting motif called the PACT domain near its C-terminus. The protein interacts with the microtubule nucleation component gamma-tubulin and is likely important to normal functioning of the centrosomes, cytoskeleton, and cell-cycle progression. Mutations in this gene cause Seckel syndrome-4 and microcephalic osteodysplastic primordial dwarfism type II. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 5116 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |