Pan-Symmetric Di-Methyl Arginine Motif Monoclonal Antibody (CAB20794)
- SKU:
- CAB20794
- Product Type:
- Antibody
- Antibody Type:
- Secondary Antibody
- Host Species:
- Donkey
- Isotype:
- Horseradish peroxidase conjugated IgG
Frequently bought together:
Description
Product Name: | Pan-Symmetric Di-Methyl Arginine Motif Monoclonal Antibody |
SKU: | CAB20794 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence containing Symmetric Di-Methyl R. |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Positive Sample: | HeLa, HCT 116, MCF7, Mouse brain, Mouse kidney, Rat brain, Rat kidney |
Conjugate: | Unconjugated |
Observed MW: | 10-180kDa |
Symmetric Dimethylarginine is a dimethylated derivative of L-arginine where the two methyl groups are attached to arginine in a symmetrical configuration. Symmetric dimethylarginine (SDMA) is formed when S-adenosylmethionine protein N-methyltransferases transfer one methyl group from S-adenosylmethionine to each of the two guanidine nitrogen groups of a single arginine residue in a protein. SDMA is released when the protein is degraded. SDMA doesn't bind nitric oxide synthase (NOS) but may noncompetitivelty inhibit nitric oxide (NO) synthesis by reducing L-arginine availability; it also may play a role in the modulation of cardiovascular homeostasis and renal function.
Purification Method: | Affinity purification |
Clone Number: | ARC51197 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |