PAK3 Rabbit Monoclonal Antibody (CAB3363)
- SKU:
- CAB3363
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- ARA
- MRX30
- MRX47
- OPHN3
- PAK-3
- PAK3beta
- bPAK
- beta-PAK
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PAK3 Rabbit Monoclonal Antibody |
SKU: | CAB3363 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PAK3 (O75914). |
Sequence: | MSDG LDNE EKPP APPL RMNS NNRD SSAL NHSS KPLP MAPE EKNK KARL RSIF PGGG DKTN KKKE KERP EISL PSDF EHTI HVGF DAVT GEFT PDLY GSQM |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | ARA; bPAK; MRX30; MRX47; OPHN3; PAK-3; XLID30; PAK3beta; beta-PAK; PAK3 |
Positive Sample: | Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytosol, endosome, glutamatergic synapse, plasma membrane, postsynaptic density |
Calculated MW: | 62kDa |
Observed MW: | 65kDa |
The protein encoded by this gene is a serine-threonine kinase and forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of a non-syndromic form of X-linked intellectual disability. Alternatively spliced transcript variants encoding different isoforms have been identified.
Purification Method: | Affinity purification |
Gene ID: | 5063 |
Clone Number: | ARC1955 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |