PAK1/PAK2/PAK3 Polyclonal Antibody (CAB21090)
- SKU:
- CAB21090
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
Product Name: | PAK1/PAK2/PAK3 Polyclonal Antibody |
SKU: | CAB21090 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 350-450 of human PAK1/PAK2/PAK3 (NP_002567.3). |
Sequence: | GSLT DVVT ETCM DEGQ IAAV CREC LQAL EFLH SNQV IHRD IKSD NILL GMDG SVKL TDFG FCAQ ITPE QSKR STMV GTPY WMAP EVVT RKAY GPKV DIWS L |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | PAKalpha; PAK1/PAK2/PAK3 |
Positive Sample: | SH-SY5Y,HeLa,MCF7,Mouse testis,Rat testis,C6 |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytosol, focal adhesion, microtubule organizing center, nuclear membrane, nucleoplasm, plasma membrane, ruffle membrane, Z disc |
Calculated MW: | 65kDa |
Observed MW: | 61kDa, 66-68kDa |
This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]
Purification Method: | Affinity purification |
Gene ID: | 5058/5062/5063 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |