The Anti-p73 Antibody (CAB2670) is a vital tool for researchers studying the p73 protein, a member of the p53 family that plays a key role in cell cycle regulation and apoptosis. This polyclonal antibody, produced in rabbits, is specifically designed for use in Western blot applications and is highly reactive with human samples.The Anti-p73 Antibody binds to the p73 protein, allowing for the detection and analysis of p73 expression in various cell types. This antibody is invaluable for research in fields such as oncology and developmental biology, where the p73 protein is known to be involved in tumor suppression and neuronal development.
By utilizing the Anti-p73 Antibody, researchers can gain insight into the function and regulation of the p73 protein, leading to a deeper understanding of its role in cellular processes and potential implications for disease. This antibody is a valuable tool for studying p73-related pathways and exploring potential therapeutic targets in various health conditions.
Product Name:
p73 Rabbit Monoclonal Antibody
SKU:
CAB2670
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human p73 (O15350).
This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined.
Purification Method:
Affinity purification
Gene ID:
7161
Clone Number:
ARC2628
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using p73 Rabbit mAb (CAB2670) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
