The Anti-p16 antibody (CAB4794) provided by AssayGenie is a high-quality polyclonal antibody designed for research involving the p16 protein. p16 is a key regulator of cell cycle progression, specifically acting as a tumor suppressor by inhibiting the activity of cyclin-dependent kinases. This antibody is raised in rabbits and has been validated for use in Western blot applications, providing researchers with a reliable tool for detecting and analyzing p16 expression in various cell types.The p16 protein is known for its role in cell senescence and the prevention of uncontrolled cell growth, making it a crucial target for studying cancer development and progression.
Aberrant expression of p16 has been linked to various types of cancer, making it a potential biomarker for early detection and prognosis. By using the Anti-p16 antibody, researchers can gain valuable insights into the mechanisms underlying cancer pathogenesis and potentially identify new therapeutic targets for treating this disease.Overall, the Anti-p16 antibody from AssayGenie offers researchers a reliable tool for studying the role of p16 in cancer and other pathological conditions. Its high reactivity with human samples and specificity for the p16 protein make it an ideal choice for immunology and cancer research studies.
Product Name:
p16-ARC/ARC16/ARPC5 Rabbit Monoclonal Antibody
SKU:
CAB4794
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human p16-ARC/ARC16/ARPC5 (O15511).
This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p16 subunit, has yet to be determined. Alternatively spliced transcript variants encoding different isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
10092
Clone Number:
ARC0221
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using p16-ARC/ARC16/ARPC5 Rabbit mAb (CAB4794) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 3min.
