The Anti-Oxytocin Receptor Antibody (CAB19740) is a highly specific tool for research involving the oxytocin receptor, a key protein involved in various physiological processes such as social bonding, reproduction, and stress regulation. This antibody, raised in rabbits, is validated for use in Western blot applications and is highly reactive with human samples. It binds specifically to the oxytocin receptor protein, enabling accurate detection and analysis in different cell types.The oxytocin receptor is a G-protein coupled receptor that plays a crucial role in mediating the effects of oxytocin, a hormone known for its role in bonding, trust, and social behavior. Dysregulation of the oxytocin receptor has been implicated in various neuropsychiatric disorders such as autism, schizophrenia, and anxiety disorders.
Studying the expression and function of the oxytocin receptor is essential for understanding its role in these conditions and developing potential therapeutic strategies.This Anti-Oxytocin Receptor Antibody is a valuable tool for researchers in the fields of neuroscience, endocrinology, and behavioral science who are investigating the role of the oxytocin receptor in health and disease. Its high specificity and reactivity make it an ideal choice for studies aiming to unravel the complex mechanisms underlying oxytocin receptor signaling and its implications for human health.
Product Name:
Oxytocin Receptor Rabbit Monoclonal Antibody
SKU:
CAB19740
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Oxytocin Receptor (P30559).
Sequence:
LLLA LSGN ACVL LALR TTRQ KHSR LFFF MKHL SIAD LVVA VFQV LPQL LWDI TFRF YGPD LLCR LVKY LQVV GMFA STYL LLLM SLDR CLAI CQPL RSLR R
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:1000
Synonyms:
OTR; OT-R; Oxytocin Receptor
Positive Sample:
HeLa,PC-3,Jukat,Mouse brain
Conjugate:
Unconjugated
Cellular Localization:
Cell membrane.
Calculated MW:
43kDa
Observed MW:
46kDa
The protein encoded by this gene belongs to the G-protein coupled receptor family and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The oxytocin-oxytocin receptor system plays an important role in the uterus during parturition.
Purification Method:
Affinity purification
Gene ID:
5021
Clone Number:
ARC2266
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Oxytocin Receptor Rabbit mAb (CAB19740) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
