The Anti-OTX1 Antibody (CAB19737) from Assay Genie is a valuable tool for researchers studying the OTX1 protein, a transcription factor involved in the development of the brain, sensory organs, and pituitary gland. This polyclonal antibody, produced in rabbits, specifically binds to the OTX1 protein in human samples, making it suitable for use in Western blotting and immunohistochemistry applications.OTX1 is known for its role in the regulation of gene expression during embryonic development, making it a key player in neurogenesis and organogenesis.
Dysregulation of OTX1 has been linked to various neurological disorders and developmental abnormalities, highlighting its importance in both normal development and disease. By using the Anti-OTX1 Antibody, researchers can study the expression and localization of OTX1 in different cell types and tissues, advancing our understanding of its functions in health and disease.
Product Name:
OTX1 Rabbit Monoclonal Antibody
SKU:
CAB19737
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human OTX1 (NP_055377.1).
This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mouse is required for proper brain and sensory organ development and can cause epilepsy. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
5013
Clone Number:
ARC2264
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using OTX1 Rabbit mAb (CAB19737) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
