The Anti-OSTE Antibody (CAB20368) is a polyclonal antibody designed for research involving OSTE, a cell surface molecule implicated in bone metabolism and osteoporosis. The antibody, raised in rabbits, is highly reactive with human samples and is validated for use in various applications including immunohistochemistry and flow cytometry. It specifically binds to the OSTE protein, enabling detection and analysis in bone cells, making it ideal for studies in bone biology and skeletal disorders.
OSTE, also known as a key regulator of bone turnover, plays a critical role in bone homeostasis by modulating osteoblast and osteoclast activities. Its significance in bone metabolism makes it a valuable target for research into diseases like osteoporosis, osteogenesis imperfecta, and other bone-related disorders. Understanding the role of OSTE is crucial for developing therapies that target bone health and overall skeletal function.
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.
Purification Method:
Affinity purification
Gene ID:
4331448
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various tissues from the japonica rice (Oryza sativa L.) variety Zhonghua 11, using OsTE Rabbit pAb (CAB20368) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
