The Anti-OSLIC1 Antibody (CAB20369) offered by Assay Genie is a highly specific and reliable tool for researchers studying the O-Linked N-Acetylglucosamine (O-GlcNAc) cycling enzyme in various cellular processes. This polyclonal antibody, produced in rabbits, is optimized for use in immunofluorescence, immunohistochemistry, and Western blotting applications.OSLIC1, also known as O-GlcNAcase, is a key enzyme involved in the removal of O-GlcNAc modifications on proteins, regulating important cellular functions such as transcription, signaling, and stress responses. Dysregulation of O-GlcNAc cycling has been implicated in various diseases including cancer, diabetes, and neurodegenerative disorders, making OSLIC1 a promising target for therapeutic interventions.
By specifically binding to OSLIC1 protein, this antibody enables researchers to detect and analyze its expression levels and localization in different cell types and tissues. With its high reactivity to human samples, the Anti-OSLIC1 Antibody is a valuable tool for investigating the role of O-GlcNAc cycling in disease pathogenesis and exploring potential therapeutic strategies targeting this enzyme.
Transcriptional activator that binds double-stranded DNA and the single-stranded RNA polymers poly(rA), poly(rU) and poly(rG), but not poly(rC). Mediates optimal plant architecture through brassinosteroid (BR) signaling. May act as a negative regulator in sterol homeostasis. Acts as negative regulator of BR signaling. Binds to the specific DNA sequence 5'-CTCGC-3' of BZR1 promoter and negatively regulates BZR1. Acts as an antagonistic transcription factor of BZR1 to attenuate the BR signaling pathway and regulate leaf bending. Represses the expression of ILI1, and activates that of IBH1 to balance the regulation activity of BZR1
Purification Method:
Affinity purification
Gene ID:
4341994
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various tissues from the japonica rice (Oryza sativa L.) variety Zhonghua 11, using OsLIC1 Rabbit pAb (CAB20369) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 300s.
