The Anti-OSGSK2 Antibody (CAB20367) is a high-quality polyclonal antibody designed for research involving OSGSK2, a key protein involved in cellular signaling pathways. This antibody is raised in rabbits and has been validated for use in various applications, including Western blot analysis.OSGSK2 is a crucial player in the regulation of glycogen synthesis and cell metabolism, making it a significant target for studies in the fields of metabolic disorders, diabetes, and cancer research. The Anti-OSGSK2 Antibody binds specifically to OSGSK2, enabling researchers to detect and analyze its expression levels in various cell types and tissues.
By using this antibody, researchers can gain valuable insights into the functions of OSGSK2 and its potential role in disease pathogenesis. Its high reactivity with human samples makes it an ideal tool for investigating the mechanisms underlying OSGSK2's involvement in cellular processes, offering new possibilities for therapeutic interventions and drug development in the future.
Serine-threonine kinase that acts as a negative regulator of brassinosteroid (BR) signaling. Phosphorylates DLT and BZR1, two positive regulators that mediates several BR responses. Phosphorylation of DLT and BZR1 inhibits their activities in BR signaling. Phosphorylates OFP8, a positive regulator of BR responses. Phosphorylated OFP8 shuttles from the nucleus to the cytoplasm where it is degraded by the proteasome. Phosphorylates the E3 ubiquitin-protein ligase PUB24, a negative regulator of BR signaling, which targets BZR1 and promotes its degradation via the 26S proteasome. Phosphorylation of PUB24 increases its stability. Phosphorylates the AP2-ERF transcription factor SMOS1, a positive regulator of BR signaling, which cooperatively functions in a transactivating complex with BZR1 to enhance the transcription of BR biosynthetic genes. Phosphorylation of SMOS1 leads to its degradation by an unknown mechanism.
Purification Method:
Affinity purification
Gene ID:
4338079
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various tissues from the japonica rice (Oryza sativa L.) variety Zhonghua 11, using OsGSK2 Rabbit pAb (CAB20367) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
