The Anti-OLIG3 Antibody (CAB0600) is a crucial tool for researchers studying OLIG3, a transcription factor involved in the development of the central nervous system. This antibody, produced by Assay Genie and validated for use in various applications including immunohistochemistry and Western blot, specifically targets the OLIG3 protein, allowing for accurate detection and analysis in a range of samples.OLIG3 plays a significant role in neural development, specifically in the differentiation of oligodendrocyte precursor cells and the regulation of myelin formation. Researchers studying neurological disorders, such as multiple sclerosis and spinal cord injuries, can benefit from using this antibody to better understand the function of OLIG3 in these conditions.
By elucidating the mechanisms of OLIG3, scientists can uncover potential therapeutic targets for treating diseases affecting the central nervous system.Overall, the Anti-OLIG3 Antibody (CAB0600) offers a reliable and specific tool for researchers interested in delving into the intricate processes of neural development and exploring potential therapeutic avenues for neurological disorders.
Product Name:
Olig3 Rabbit Monoclonal Antibody
SKU:
CAB0600
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 173-272 of human Olig3 (Q7RTU3).
Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in neuron differentiation and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II; spinal cord motor neuron cell fate specification; and spinal cord motor neuron migration. Predicted to be part of chromatin. Predicted to be active in nucleus.
Purification Method:
Affinity purification
Gene ID:
167826
Clone Number:
ARC2524
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of U-251 MG cells, using Olig3 antibody (CAB0600) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
