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NUDT5 Rabbit Monoclonal Antibody (CAB0609)

SKU:
CAB0609
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
NUDT5
YSA1
YSA1H
YSAH1
hNUDT5
nudix hydrolase 5
Research Area:
Cell Biology
$167 - $503
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:NUDT5 Rabbit Monoclonal Antibody
SKU:CAB0609
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human NUDT5 (Q9UKK9).
Sequence:MESQ EPTE SSQN GKQY IISE ELIS EGKW VKLE KTTY MDPT GKTR TWES VKRT TRKE QTAD GVAV IPVL QRTL HYEC IVLV KQFR PPMG GYCI EFPA GLID
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200
Synonyms:YSA1; YSA1H; YSAH1; hNUDT5; NUDT5
Positive Sample:HeLa,HepG2,A-431,Mouse thymus,Mouse liver,Rat kidney
Conjugate:Unmodified
Cellular Localization:Cytosol, Extracellular Exosome, Nucleus
Calculated MW:24kDa
Observed MW:34kDa

This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates, including ADP-ribose (ADPR) and 8-oxoGua-containing 8-oxo-dADP and 8-oxo-dGDP. Protein-bound ADP ribose can be hazardous to the cell because it can modify some amino acid residues, resulting in the inhibition of ATP-activated potassium channels. 8-oxoGua is an oxidized form of guanine that can potentially alter genetic information by pairing with adenine and cytosine in RNA. Presence of 8-oxoGua in RNA results in formation of abnormal proteins due to translational errors.

Purification Method:Affinity purification
Gene ID:11164
Clone Number:ARC2525
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using NUDT5 antibody (CAB0609) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.

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