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NRCAM Rabbit Polyclonal Antibody (CAB20160)

SKU:
CAB20160
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
$167 - $503
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:NRCAM Rabbit Polyclonal Antibody
SKU:CAB20160
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 25-115 of human NRCAM (Q92823).
Sequence:QMIS ALEV PLDP KLLE DLVQ PPTI TQQS PKDY IIDP RENI VIQC EAKG KPPP SFSW TRNG THFD IDKD PLVT MKPG TGTL IINI MSEG KAE
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:NEDNMS; NRCAM
Positive Sample:SH-SY5Y,Mouse spinal cord,Mouse brain
Conjugate:Unconjugated
Cellular Localization:axon, external side of plasma membrane, extracellular region, glutamatergic synapse, neuron projection, plasma membrane, postsynaptic density membrane
Calculated MW:144kDa
Observed MW:140kDa

Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily. This gene encodes a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains. This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. This gene is also expressed in non-neural tissues and may play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration. Allelic variants of this gene have been associated with autism and addiction vulnerability. Alternative splicing results in multiple transcript variants encoding different isoforms.

Purification Method:Affinity purification
Gene ID:4897
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using NRCAM Rabbit pAb (CAB20160) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.

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