NRCAM Rabbit Polyclonal Antibody (CAB20160)
- SKU:
- CAB20160
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
Product Name: | NRCAM Rabbit Polyclonal Antibody |
SKU: | CAB20160 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-115 of human NRCAM (Q92823). |
Sequence: | QMIS ALEV PLDP KLLE DLVQ PPTI TQQS PKDY IIDP RENI VIQC EAKG KPPP SFSW TRNG THFD IDKD PLVT MKPG TGTL IINI MSEG KAE |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | NEDNMS; NRCAM |
Positive Sample: | SH-SY5Y,Mouse spinal cord,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | axon, external side of plasma membrane, extracellular region, glutamatergic synapse, neuron projection, plasma membrane, postsynaptic density membrane |
Calculated MW: | 144kDa |
Observed MW: | 140kDa |
Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily. This gene encodes a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains. This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. This gene is also expressed in non-neural tissues and may play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration. Allelic variants of this gene have been associated with autism and addiction vulnerability. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 4897 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |