The NOP56 Polyclonal Antibody (CAB18693) is a valuable tool for researchers studying the NOP56 protein, which plays a crucial role in RNA processing and ribosome biogenesis. This antibody, raised in rabbits, is highly specific to human samples and is suitable for Western blot applications. By targeting the NOP56 protein, this antibody enables the detection and analysis of NOP56 in various cell types, making it an essential reagent for studies in molecular biology and genetics.NOP56 is a key player in RNA modification and ribosome assembly, making it an important target for research into gene expression and protein synthesis.
Dysregulation of NOP56 has been implicated in a variety of diseases, including cancer and neurodegenerative disorders, highlighting its potential as a therapeutic target. By investigating the function of NOP56, researchers can gain valuable insights into the mechanisms underlying these conditions and potentially identify novel treatment strategies.
Product Name:
NOP56 Rabbit Polyclonal Antibody
SKU:
CAB18693
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human NOP56 (NP_006383.2).
Nop56p is a yeast nucleolar protein that is part of a complex with the nucleolar proteins Nop58p and fibrillarin. Nop56p is required for assembly of the 60S ribosomal subunit and is involved in pre-rRNA processing. The protein encoded by this gene is similar in sequence to Nop56p and is also found in the nucleolus. Expansion of a GGCCTG repeat from 3-8 copies to 1500-2500 copies in an intron of this gene results in spinocerebellar ataxia 36. Multiple transcript variants encoding several different isoforms have been found for this gene, but the full-length nature of most of them has not been determined.
Purification Method:
Affinity purification
Gene ID:
10528
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NOP56 Rabbit pAb (CAB18693) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
