The NKX6-1 Polyclonal Antibody (CAB20419) is a valuable tool for researchers studying NKX6-1, a transcription factor essential for the development and function of pancreatic beta cells. This antibody is produced in rabbits and is highly specific for human samples, making it ideal for use in experiments such as Western blotting.NKX6-1 is known for its role in regulating insulin production and glucose metabolism, making it a key player in understanding diseases like diabetes.
By targeting the NKX6-1 protein, researchers can gain insights into the molecular mechanisms governing beta cell development and function, paving the way for potential therapeutic interventions in diabetes and other related conditions.With its high reactivity and specificity, the NKX6-1 Polyclonal Antibody (CAB20419) is a valuable tool for studying the role of NKX6-1 in pancreatic biology and disease, driving advancements in diabetes research and treatment strategies.
Product Name:
NKX6-1 Rabbit Polyclonal Antibody
SKU:
CAB20419
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human NKX6-1 (NP_006159.2).
In the pancreas, NKX6.1 is required for the development of beta cells and is a potent bifunctional transcription regulator that binds to AT-rich sequences within the promoter region of target genes Iype et al. (2004) [PubMed 15056733].
Purification Method:
Affinity purification
Gene ID:
4825
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded mouse pancreas using NKX6-1 Rabbit pAb (CAB20419) at dilution of 1:50 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
