The NKX3.1 Polyclonal Antibody (CAB19734) is a valuable tool for researchers studying NKX3.1, a critical transcription factor involved in prostate development and tumorigenesis. This antibody, developed using rabbit immunization, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the NKX3.1 protein, this antibody allows for the detection and analysis of NKX3.1 expression in various cell types, making it ideal for investigations in the fields of oncology and developmental biology.
NKX3.1 plays a crucial role in regulating prostate epithelial cell differentiation and has been implicated in the pathogenesis of prostate cancer. Understanding the function and expression of NKX3.1 is essential for deciphering the molecular mechanisms underlying prostate development and disease progression. Research using this antibody may provide valuable insights into potential therapeutic strategies targeting NKX3.1 in prostate cancer and other related conditions.
Product Name:
NKX3.1 Rabbit Monoclonal Antibody
SKU:
CAB19734
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-234 of human NKX3.1 (Q99801).
This gene encodes a homeobox-containing transcription factor. This transcription factor functions as a negative regulator of epithelial cell growth in prostate tissue. Aberrant expression of this gene is associated with prostate tumor progression. Alternate splicing results in multiple transcript variants of this gene.
Purification Method:
Affinity purification
Gene ID:
4824
Clone Number:
ARC2261
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using NKX3.1 Rabbit mAb (CAB19734) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
