The Anti-NG2/CSPG4 Antibody (CAB21095) is a powerful tool for researchers studying NG2/CSPG4, a cell surface proteoglycan involved in various cellular processes, including cell adhesion, migration, and proliferation. This antibody, produced in rabbits, exhibits high specificity and sensitivity for human samples and has been validated for use in multiple applications, including immunohistochemistry, immunofluorescence, and flow cytometry.NG2/CSPG4 is a key player in cancer progression, as it is overexpressed in various cancer types and is associated with tumor growth, invasion, and angiogenesis. Its role in promoting cancer cell survival and metastasis makes it an attractive target for developing novel cancer therapies.
By using the Anti-NG2/CSPG4 Antibody, researchers can investigate the expression and localization of NG2/CSPG4 in cancer cells and tumor tissues, providing valuable insights into the mechanisms underlying cancer progression.Furthermore, NG2/CSPG4 has also been implicated in other pathological conditions, such as neurodegenerative diseases and fibrosis. The Anti-NG2/CSPG4 Antibody offers researchers the opportunity to explore the role of NG2/CSPG4 in these diseases and uncover potential therapeutic targets for intervention. Its versatility and reliability make it a valuable tool for advancing our understanding of NG2/CSPG4 biology and its implications in various pathophysiological processes.
Product Name:
NG2/CSPG4 Monoclonal Antibody
SKU:
CAB21095
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1340-1563 of human NG2/CSPG4 (NP_001888.2).
Apical cell membrane, Cell projection, Extracellular side, Single-pass type I membrane protein, lamellipodium membrane.
Calculated MW:
251kDa
Observed MW:
250-450kDa
A human melanoma-associated chondroitin sulfate proteoglycan plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. CSPG4 represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells.
Purification Method:
Affinity purification
Gene ID:
1464
Clone Number:
ARC52162
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of A375, using NG2/CSPG4 antibody (CAB21095) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
