NF-κB2 Rabbit Monoclonal Antibody (CAB19605)
- SKU:
- CAB19605
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | NF-κB2 Rabbit Monoclonal Antibody |
SKU: | CAB19605 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 745-877 of human NF-κB2 (Q00653). |
Sequence: | LLLN AAQN TMEP PLTP PSPA GPGL SLGD TALQ NLEQ LLDG PEAQ GSWA ELAE RLGL RSLV DTYR QTTS PSGS LLRS YELA GGDL AGLL EALS DMGL EEGV RLLR GPET RDKL PSTA EVKE DSAY GSQS VEQE A |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | p52; p100; H2TF1; LYT10; CVID10; LYT-10; NF-kB2; p49/p100; NF-κB2 |
Positive Sample: | THP-1,MCF7,HeLa,NIH/3T3,C6,Mouse thymus |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 97kDa |
Observed MW: | 120kDa |
This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 4791 |
Clone Number: | ARC0084 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |