NF-κB2 Rabbit Polyclonal Antibody (CAB11163)
- SKU:
- CAB11163
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | NF-κB2 Rabbit Polyclonal Antibody |
SKU: | CAB11163 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 690-899 of human NF-κB2 (NP_002493.3). |
Sequence: | AGAD IHAE NEEP LCPL PSPP TSDS DSDS EGPE KDTR SSFR GHTP LDLT CSTK VKTL LLNA AQNT MEPP LTPP SPAG PGLS LGDT ALQN LEQL LDGP EAQG SWAE LAER LGLR SLVD TYRQ TTSP SGSL LRSY ELAG GDLA GLLE ALSD MGLE EGVR LLRG PETR DKLP STEV KEDS AYGS QSVE QEAE KLGP PPEP PGGL CHGH PQPQ VH |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | p52; p100; H2TF1; LYT10; CVID10; LYT-10; NF-kB2; p49/p100; NF-κB2 |
Positive Sample: | Jurkat,MCF7,NCI-H460,Mouse thymus |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 97kDa |
Observed MW: | 125kDa |
This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 4791 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |