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Nesprin 1 Rabbit Polyclonal Antibody (CAB20256)

SKU:
CAB20256
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
8B
AMC3
AMCM
CPG2
ARCA1
EDMD4
KASH1
MYNE1
Nesp1
SCAR8
C6orf98
dJ45H2.2
$167 - $503
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Nesprin 1 Rabbit Polyclonal Antibody
SKU:CAB20256
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 8220-8410 of human Nesprin 1 (NP_892006.3).
Sequence:HDLS DREL ELED SAAL SDLH WHDR SADS LLSP QPSS NLSL SLAQ PLRS ERSG RDTP ASVD SIPL EWDH DYDL SRDL ESAM SRAL PSED EEGQ DDKD FYLR GAVG LSGD HSAL ESQI RQLG KALD DSRF QIQQ TENI IRSK TPTG PELD TSYK GYMK LLGE CSSS IDSV KRLE HKLK EEEE SLPG FVNL HST
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200
Synonyms:8B; AMC3; AMCM; CPG2; ARCA1; EDMD4; KASH1; MYNE1; Nesp1; SCAR8; C6orf98; dJ45H2.2; Nesprin 1
Positive Sample:Mouse skeletal muscle
Conjugate:Unconjugated
Cellular Localization:cytoplasm, cytoskeleton, Golgi apparatus, nuclear envelope, nuclear membrane, nucleolus, nucleoplasm, nucleus, P-body, sarcomere
Calculated MW:1011kDa
Observed MW:131kDa

This gene encodes a spectrin repeat containing protein expressed in skeletal and smooth muscle, and peripheral blood lymphocytes, that localizes to the nuclear membrane. Mutations in this gene have been associated with autosomal recessive spinocerebellar ataxia 8, also referred to as autosomal recessive cerebellar ataxia type 1 or recessive ataxia of Beauce. Alternatively spliced transcript variants encoding different isoforms have been described.

Purification Method:Affinity purification
Gene ID:23345
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from Mouse skeletal muscle, using Nesprin 1 Rabbit pAb (CAB20256) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.

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