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Nesprin 1 Rabbit Monoclonal Antibody (CAB19781)

SKU:
CAB19781
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
8B
ARCA1
C6orf98
CPG2
EDMD4
KASH1
MYNE1
Nesp1
SCAR8
dJ45H2.2
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Nesprin 1 Rabbit Monoclonal Antibody
SKU:CAB19781
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 8200-8400 of human Nesprin 1 (Q8NF91).
Sequence:FGRV ERYH KKLI RLPL PDDE HDLS DREL ELED SAAL SDLH WHDR SADS LLSP QPSS NLSL SLAQ PLRS ERSG RDTP ASVD SIPL EWDH DYDL SRDL ESAM SRAL PSED EEGQ DDKD FYLR GAVG LSGD HSAL ESQI RQLG KALD DSRF QIQQ TENI IRSK TPTG PELD TSYK GYMK LLGE CSSS IDSV KRLE HKLK EEEE S
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200
Synonyms:8B; AMC3; AMCM; CPG2; ARCA1; EDMD4; KASH1; MYNE1; Nesp1; SCAR8; C6orf98; dJ45H2.2; Nesprin 1
Positive Sample:HeLa,A-549,HeLa,A549
Conjugate:Unconjugated
Cellular Localization:cytoplasm, cytoskeleton, Golgi apparatus, nuclear envelope, nuclear membrane, nucleolus, nucleoplasm, nucleus, P-body, sarcomere
Calculated MW:1011kDa/112kDa
Observed MW:112kDa/110kDa

This gene encodes a spectrin repeat containing protein expressed in skeletal and smooth muscle, and peripheral blood lymphocytes, that localizes to the nuclear membrane. Mutations in this gene have been associated with autosomal recessive spinocerebellar ataxia 8, also referred to as autosomal recessive cerebellar ataxia type 1 or recessive ataxia of Beauce. Alternatively spliced transcript variants encoding different isoforms have been described.

Purification Method:Affinity purification
Gene ID:23345
Clone Number:ARC2307
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using Nesprin 1 Rabbit mAb (CAB19781) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates / proteins: 25 μg per lane.Blocking buffer: 3 % nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.

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