The NELL2 Polyclonal Antibody (CAB19327) is a valuable tool for researchers studying NELL2, a protein that plays a role in neuronal development and function. This antibody, raised in rabbits, specifically targets NELL2 in human samples and is validated for use in Western blot applications. By binding to the NELL2 protein, this antibody allows for the detection and analysis of NELL2 expression in various cell types, making it ideal for research in neuroscience and neurobiology.NELL2 is known to be involved in neuronal growth, differentiation, and synaptic plasticity, making it a key player in the development and maintenance of the nervous system.
Studies have shown that dysregulation of NELL2 expression may be linked to neurological disorders and neurodegenerative diseases. As such, understanding the function of NELL2 is essential for advancing our knowledge of these conditions and potentially developing targeted therapies.Overall, the NELL2 Polyclonal Antibody is a valuable tool for researchers looking to explore the role of NELL2 in the nervous system and its implications in neurological disorders. Its high reactivity and specificity make it a reliable choice for investigations into this important protein.
Product Name:
NELL2 Rabbit Polyclonal Antibody
SKU:
CAB19327
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 22-300 of human NELL2 (NP_006150.1).
The protein encoded by this gene is a glycoprotein containing several von Willebrand factor C domains and epidermal growth factor (EGF)-like domains. The encoded protein acts as a homotrimer and is found in the cytoplasm. Several variants encoding a few different isoforms exist, and at least one isoform appears to be a secreted protein. Studies in mouse suggest that this protein plays a role in neural cell growth and differentiation as well as in oncogenesis.
Purification Method:
Affinity purification
Gene ID:
4753
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NELL2 Rabbit pAb (CAB19327) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
