In a similar fashion, the Anti-NDUFS4 Antibody (CAB8691) is a valuable tool for researchers studying NDUFS4, a key subunit of mitochondrial complex I involved in oxidative phosphorylation. This polyclonal antibody, generated in rabbits, has high specificity for human samples and is optimized for use in Western blotting techniques. By targeting the NDUFS4 protein, this antibody enables researchers to investigate the role of mitochondrial complex I in various cell types, offering insights into bioenergetics and mitochondrial dysfunction in diseases such as neurodegenerative disorders and metabolic conditions.NDUFS4 is essential for maintaining mitochondrial function and energy production, making it a key player in cellular metabolism and ATP generation.
Dysregulation of NDUFS4 has been linked to a range of pathological conditions, underscoring the importance of studying its function in disease states. By characterizing the expression and activity of NDUFS4, researchers can uncover potential therapeutic targets and interventions for mitochondrial disorders and related diseases.Overall, the Anti-NDUFS4 Antibody (CAB8691) provides researchers with a powerful tool for investigating the role of NDUFS4 in cellular bioenergetics and mitochondrial physiology. Its specificity and reliability make it an invaluable resource for studies on mitochondrial function and dysfunction, paving the way for innovative research and potential therapeutic advancements in mitochondrial-related disorders.
Product Name:
NDUFS4 Rabbit Monoclonal Antibody
SKU:
CAB8691
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human NDUFS4 (O43181).
This gene encodes an nuclear-encoded accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I, or NADH:ubiquinone oxidoreductase). Complex I removes electrons from NADH and passes them to the electron acceptor ubiquinone. Mutations in this gene can cause mitochondrial complex I deficiencies such as Leigh syndrome. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
4724
Clone Number:
ARC1784
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using NDUFS4 Rabbit mAb (CAB8691) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
