The NDUFB8 Polyclonal Antibody (CAB20457) is a valuable tool for researchers studying the NDUFB8 protein, a subunit of the mitochondrial respiratory chain complex I. This antibody, produced in rabbits, is highly specific for human samples and is validated for use in Western blot applications. By binding to NDUFB8, the antibody enables precise detection and analysis of this important protein in various cell types.NDUFB8 is essential for the assembly and function of complex I in the electron transport chain, making it a key player in cellular energy production. Dysregulation of complex I has been implicated in various human diseases, including neurodegenerative disorders and metabolic syndromes.
Understanding the role of NDUFB8 in these conditions is crucial for the development of potential therapeutic interventions targeting mitochondrial dysfunction.Researchers in the fields of biochemistry, molecular biology, and mitochondrial physiology will find the NDUFB8 Polyclonal Antibody (CAB20457) to be a valuable asset in their studies. Its high specificity and reliability make it an ideal choice for investigating the function and regulation of NDUFB8 in both normal physiological processes and disease states.
Product Name:
NDUFB8 Rabbit Polyclonal Antibody
SKU:
CAB20457
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 29-186 of human NDUFB8 (NP_004995.1).
Involved in mitochondrial respiratory chain complex I assembly. Located in endoplasmic reticulum and mitochondrion. Part of mitochondrial respiratory chain complex I. Implicated in nuclear type mitochondrial complex I deficiency 32. Biomarker of Alzheimer's disease and Parkinson's disease.
Purification Method:
Affinity purification
Gene ID:
4714
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NDUFB8 Rabbit pAb (CAB20457) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
