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N4BP2 Rabbit Polyclonal Antibody (CAB20480)

SKU:
CAB20480
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Rat
Host Species:
Rabbit
Isotype:
IgG
$167 - $503
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:N4BP2 Rabbit Polyclonal Antibody
SKU:CAB20480
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 190-320 of human N4BP2 (NP_060647.2).
Sequence:IFST QNMN LNGE NLEN SGST LSLN PLPS HSVL NESK CFIK DNTL ALES NYPE DSLL SSSL NVAS DSIA GCSS LNQK QKEL LESE CVEA QFSE APVD LDAS EPQA CLNL PGLD LPGT GGDQ KSTR VSDV FLP
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200
Synonyms:B3BP; N4BP2
Positive Sample:Rat large intestine
Conjugate:Unconjugated
Cellular Localization:cytosol
Calculated MW:199kDa
Observed MW:199kDa

This gene encodes a protein containing a polynucleotide kinase domain (PNK) near the N-terminal region, and a Small MutS Related (Smr) domain near the C-terminal region. The encoded protein can bind to both B-cell leukemia/lymphoma 3 (BCL-3) and neural precursor cell expressed, developmentally downregulated 4, (Nedd4) proteins. This protein binds and hydrolyzes ATP, may function as a 5'-polynucleotide kinase, and has the capacity to be a ubiquitylation substrate. This protein may play a role in transcription-coupled DNA repair or genetic recombination. Alternative splicing results in multiple transcript variants encoding different isoforms.

Purification Method:Affinity purification
Gene ID:55728
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of Rat large intestine, using N4BP2 antibody (CAB20480) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.

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