The Myom2 Monoclonal Antibody (CAB20526) is a valuable tool for researchers studying the Myomesin-2 (Myom2) protein, a key component of the sarcomere in muscle cells. This antibody, produced in mice, is highly specific to Myom2 and is validated for use in immunofluorescence and immunohistochemistry applications.Myom2 is essential for maintaining the structure and function of muscle cells, playing a crucial role in muscle contraction and overall muscle physiology. Dysregulation of Myom2 has been linked to muscle disorders and myopathies, making it an important target for research in muscle biology and disease.
By using the Myom2 Monoclonal Antibody, researchers can accurately detect and visualize Myom2 in various tissue samples, providing valuable insights into its localization and expression levels. This antibody is a valuable tool for understanding the role of Myom2 in muscle function and pathology, with potential implications for the development of therapies for muscle-related diseases.
Product Name:
MYOM2 Rabbit Polyclonal Antibody
SKU:
CAB20526
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human MYOM2 (NP_003961.3).
The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD and 165 kD. The predicted MYOM2 protein contains 1,465 amino acids. Like MYOM1, MYOM2 has a unique N-terminal domain followed by 12 repeat domains with strong homology to either fibronectin type III or immunoglobulin C2 domains. Protein sequence comparisons suggested that the MYOM2 protein and bovine M protein are identical.
Purification Method:
Affinity purification
Gene ID:
9172
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MYOM2 Rabbit pAb (CAB20526) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
