The MYH7B Monoclonal Antibody (CAB19246) is a cutting-edge tool for researchers studying the MYH7B protein, a key player in muscle contraction and development. This antibody, produced in mice, exhibits high specificity and sensitivity for detecting MYH7B in human samples, making it ideal for use in various experimental techniques such as Western blotting and immunofluorescence.MYH7B, a member of the myosin superfamily, is known for its role in striated muscle contraction and its involvement in muscle fiber development.
Research on MYH7B has implications in understanding muscle disorders, such as myopathies and muscular dystrophies, as well as in studying muscle regeneration post-injury.By utilizing the MYH7B Monoclonal Antibody, researchers can gain valuable insights into the function and regulation of MYH7B in various cell types and tissues. This information is essential for advancing knowledge in muscle biology and may lead to the development of novel therapeutic approaches for muscle-related conditions.
Product Name:
MYH7B Rabbit Monoclonal Antibody
SKU:
CAB19246
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1750-1983 of human MYH7B (NP_065935.3).
The myosin II molecule is a multi-subunit complex consisting of two heavy chains and four light chains. This gene encodes a heavy chain of myosin II, which is a member of the motor-domain superfamily. The heavy chain includes a globular motor domain, which catalyzes ATP hydrolysis and interacts with actin, and a tail domain in which heptad repeat sequences promote dimerization by interacting to form a rod-like alpha-helical coiled coil. This heavy chain subunit is a slow-twitch myosin. Alternatively spliced transcript variants have been found, but the full-length nature of these variants is not determined.
Purification Method:
Affinity purification
Gene ID:
57644
Clone Number:
ARC2406
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of Mouse skeletal muscle, using MYH7B antibody (CAB19246) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
