The Anti-MVP Antibody (CAB1039) is a high-quality antibody designed for research involving the MVP protein, a crucial player in cellular processes such as drug resistance and tumorigenesis. This polyclonal antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in various applications, including Western blot and immunohistochemistry.MVP, also known as Major Vault Protein, is involved in multidrug resistance and is associated with poor prognosis in cancer patients. Research on MVP is essential for understanding drug resistance mechanisms and developing new approaches to overcome this challenge in cancer treatment.
The Anti-MVP Antibody provides a valuable tool for studying the expression and localization of MVP in different cell types and tissues, making it ideal for investigations in oncology and drug development. By targeting MVP, researchers can gain insights into mechanisms of drug resistance and identify new therapeutic strategies for improving cancer treatment outcomes. The Anti-MVP Antibody is a reliable reagent for studies aimed at elucidating the role of MVP in cancer biology and advancing personalized medicine approaches for patients with drug-resistant tumors.
Product Name:
MVP Rabbit Monoclonal Antibody
SKU:
CAB1039
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MVP (Q14764).
This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
9961
Clone Number:
ARC1855
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using MVP Rabbit mAb (CAB1039) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
