The Anti-MVD Antibody (CAB0813) is a high-quality polyclonal antibody designed for research involving MVD, a key enzyme involved in the biosynthesis of isoprenoids. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in a variety of applications, including Western blotting.MVD, also known as mevalonate diphosphate decarboxylase, plays a crucial role in the mevalonate pathway, which is essential for the production of cholesterol, steroid hormones, and other important molecules in the body.
Dysregulation of the mevalonate pathway has been implicated in various diseases, including cancer, cardiovascular disease, and metabolic disorders.This antibody specifically binds to the MVD protein, allowing for the detection and analysis of MVD levels in different cell types and tissues. Its versatility and specificity make it an ideal tool for researchers studying the role of MVD in health and disease, as well as for those investigating potential therapeutic strategies targeting the mevalonate pathway.
Product Name:
MVD Rabbit Monoclonal Antibody
SKU:
CAB0813
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 250-350 of human MVD (P53602).
The enzyme mevalonate pyrophosphate decarboxylase catalyzes the conversion of mevalonate pyrophosphate into isopentenyl pyrophosphate in one of the early steps in cholesterol biosynthesis. It decarboxylates and dehydrates its substrate while hydrolyzing ATP.
Purification Method:
Affinity purification
Gene ID:
4597
Clone Number:
ARC2541
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MVD antibody (CAB0813) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
