The Anti-MUC1 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0316) is a cutting-edge tool for researchers studying the MUC1 protein, a cell surface glycoprotein involved in cell adhesion and signaling pathways. This antibody, developed using advanced technology, offers high specificity and sensitivity for MUC1 detection in various sample types, including human tissue. With its unique chimeric structure, this antibody provides superior binding affinity to the MUC1 protein, enabling accurate and reliable results in experiments such as immunohistochemistry and flow cytometry.
Its exceptional performance in MUC1 detection makes it an essential tool for studies in oncology, particularly in understanding the role of MUC1 in cancer progression and metastasis.The Anti-MUC1 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0316) opens up new possibilities for researchers to delve deeper into the functions and mechanisms of MUC1 in disease development and progression. Its versatility and reliability make it a valuable asset in advancing our knowledge of MUC1 biology and its potential as a therapeutic target in cancer and other diseases.
SKU:
HDAB0316
Size:
100 µg
Clonality:
Monoclonal
Clone:
DMC493
Synonyms:
ADMCKD, ADMCKD1, CA 15-3, CD227, EMA, H23AG, KL-6, MAM6, MCD, MCKD, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM
Applications:
Flow Cyt
Recommended Dilution:
Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit/Human Fc chimeric IgG1
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.
