The Anti-MT-ND1 Antibody (CAB9743) is a high-quality polyclonal antibody designed for research involving MT-ND1, a protein encoded by the ND1 gene located in the mitochondria. This antibody, produced in rabbits, has been shown to be highly reactive with human samples and is validated for use in applications such as Western blot and immunohistochemistry.MT-ND1 is a subunit of the mitochondrial respiratory chain complex I, which plays a crucial role in the process of oxidative phosphorylation and ATP production. Dysfunctions in this complex have been associated with various mitochondrial diseases, making MT-ND1 a key target for research in areas such as mitochondrial biology, neurodegenerative diseases, and metabolic disorders.
By specifically binding to MT-ND1, this antibody enables the detection and analysis of the protein in different cell types and tissues, providing valuable insights into its function and potential implications in disease mechanisms. Its versatility and reliability make it an ideal tool for studies in cellular metabolism, bioenergetics, and mitochondrial dysfunction, offering researchers the opportunity to deepen their understanding of mitochondrial biology and explore new therapeutic strategies for related disorders.
Product Name:
MT-ND1 Rabbit mAb
Product Code:
CAB9743
Size:
20uL, 50uL, 100uL
Synonyms:
MTND1
Applications:
WB
Reactivity:
Mouse, Rat
Host Species:
Rabbit
Immunogen:
A synthesized peptide derived from human MT-ND1
Applications:
WB
Recommended Dilutions:
WB 1:500 - 1:2000
Reactivity:
Mouse, Rat
Positive Samples:
Mouse kidney, Rat brain, Rat kidney
Immunogen:
A synthesized peptide derived from human MT-ND1
Purification Method:
Affinity purification
Storage:
Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:
IgG
Sequence:
Email for sequence
Gene ID:
4535
Uniprot:
P03886
Calculated MW:
38kDa
Observed MW:
35KDa
UniProt Protein Function:
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
