The MST4 Polyclonal Antibody (CAB20964) is specifically designed for research involving MST4, a serine/threonine kinase involved in various cellular processes such as cell migration and cytoskeletal rearrangement. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to MST4, the antibody enables the detection and analysis of this protein in different cell types, making it a valuable tool for studies in cell biology and cancer research.MST4, also known as mammalian sterile 20-like kinase 4, plays a crucial role in signaling pathways that control cell growth, proliferation, and survival.
Dysregulation of MST4 has been linked to tumorigenesis and metastasis, making it a potential therapeutic target for cancer treatment. Understanding the function of MST4 is essential for developing targeted therapies that can inhibit its oncogenic effects and improve patient outcomes.Overall, the MST4 Polyclonal Antibody is a reliable tool for researchers studying the role of MST4 in cellular processes and cancer progression. Its high specificity and sensitivity make it suitable for a wide range of experimental applications, providing valuable insights into the mechanisms underlying MST4-mediated signaling pathways.
Product Name:
MST4 Monoclonal Antibody
SKU:
CAB20964
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 317-416 of human MST4 (Q9P289).
The product of this gene is a member of the GCK group III family of kinases, which are a subset of the Ste20-like kinases. The encoded protein contains an amino-terminal kinase domain, and a carboxy-terminal regulatory domain that mediates homodimerization. The protein kinase localizes to the Golgi apparatus and is specifically activated by binding to the Golgi matrix protein GM130. It is also cleaved by caspase-3 in vitro, and may function in the apoptotic pathway. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Purification Method:
Affinity purification
Gene ID:
51765
Clone Number:
ARC2953
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using MST4 Rabbit mAb (CAB20964) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
