The MRRF Polyclonal Antibody (CAB2443) is a valuable tool for researchers studying the MRRF protein, a key component of the mitochondrial ribosome involved in protein synthesis. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.MRRF, also known as Mitochondrial Ribosome Recycling Factor, plays a crucial role in maintaining the functionality of the mitochondrial ribosome, which is essential for proper cellular function. Dysregulation of MRRF has been linked to various mitochondrial disorders and diseases, making it a target of interest in research on mitochondrial biology and disease pathology.
By targeting the MRRF protein, researchers can gain valuable insights into the mechanisms underlying mitochondrial protein synthesis and its implications for health and disease. The MRRF Polyclonal Antibody (CAB2443) provides a reliable tool for detecting and analyzing MRRF expression in various cell types, making it an ideal choice for studies in mitochondrial biology and related fields.
Product Name:
MRRF Rabbit Monoclonal Antibody
SKU:
CAB2443
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 163-262 of human MRRF (Q96E11).
293T, Mouse testis, Mouse heart, Rat testis, Rat heart
Conjugate:
Unmodified
Cellular Localization:
Mitochondrial matrix, Mitochondrion
Calculated MW:
29kDa
Observed MW:
29kDa
This gene encodes a ribosome recycling factor, which is a component of the mitochondrial translational machinery. The encoded protein, along with mitochondrial elongation factor 2, functions in ribosomal recycling at the termination of mitochondrial translation by mediating the disassembly of ribosomes from messenger RNA. A pseudogene of this gene has been identified on chromosome X.
Purification Method:
Affinity purification
Gene ID:
92399
Clone Number:
ARC2589
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MRRF antibody (CAB2443) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
