MRP1 Rabbit Monoclonal Antibody (CAB2223)
- SKU:
- CAB2223
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- ABC29
- ABCC
- GS-X
- MRP
- MRP1
Description
Product Name: | MRP1 Rabbit Monoclonal Antibody |
SKU: | CAB2223 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 210-304 of human MRP1/ABCC1 (NP_004987.2). |
Sequence: | ESSA SFLS RITF WWIT GLIV RGYR QPLE GSDL WSLN KEDT SEQV VPVL VKNW KKEC AKTR KQPV KVVY SSKD PAQP KESS KVDA NEEV EALI VKS |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | MRP; ABCC; GS-X; MRP1; ABC29; DFNA77; MRP1/ABCC1 |
Positive Sample: | A549,Mouse lung,Rat skeletal muscle,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | apical plasma membrane, basal plasma membrane, basolateral plasma membrane, extracellular exosome, lateral plasma membrane, plasma membrane |
Calculated MW: | 172kDa |
Observed MW: | 170-220kDa |
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown.
Purification Method: | Affinity purification |
Gene ID: | 4363 |
Clone Number: | ARC52207 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |