The MRAS Polyclonal Antibody (CAB20958) is a valuable tool for research involving the MRAS protein, a member of the Ras family of small GTPases. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the MRAS protein, this antibody allows for the detection and analysis of MRAS in various cell types, making it ideal for studies in cell signaling pathways and cancer research.MRAS plays a key role in regulating cell growth, differentiation, and survival by activating downstream signaling cascades.
Dysregulation of MRAS has been implicated in various diseases, including cancer and developmental disorders. Understanding the function of MRAS is essential for elucidating its role in these pathological processes and identifying potential therapeutic targets.Overall, the MRAS Polyclonal Antibody (CAB20958) is a valuable tool for researchers studying the role of MRAS in cellular processes and disease development. Its high specificity and sensitivity make it a reliable option for Western blot analysis, providing valuable insights into the biology of the MRAS protein.
Product Name:
Mras Monoclonal Antibody
SKU:
CAB20958
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 109-208 of human Mras (O14807).
This gene encodes a member of the Ras family of small GTPases. These membrane-associated proteins function as signal transducers in multiple processes including cell growth and differentiation, and dysregulation of Ras signaling has been associated with many types of cancer. The encoded protein may play a role in the tumor necrosis factor-alpha and MAP kinase signaling pathways. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
22808
Clone Number:
ARC2946
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Mras antibody (CAB20958) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
