The Anti-MPO Antibody (CAB1374) offered by Assay Genie is a high-quality polyclonal antibody designed for research involving Myeloperoxidase (MPO), an enzyme found in neutrophil granulocytes. This antibody, generated in rabbits, has high specificity and sensitivity for detecting MPO in human samples, making it ideal for use in various research applications such as Western blot and immunohistochemistry.MPO is an enzyme involved in the immune response, playing a crucial role in the defense against pathogens by generating reactive oxygen species. Abnormalities in MPO activity have been implicated in various inflammatory and autoimmune diseases, making it a valuable target for research.
The Anti-MPO Antibody allows for the detection and analysis of MPO expression in different cell types, providing valuable insights into its role in immune regulation and disease pathogenesis.Researchers studying diseases such as vasculitis, arthritis, and cardiovascular disorders will find the Anti-MPO Antibody to be a valuable tool for their investigations. With its high reactivity and specificity, this antibody enables precise and reliable detection of MPO, aiding in the advancement of scientific understanding and the development of potential therapeutic interventions.
Product Name:
MPO Rabbit Polyclonal Antibody
SKU:
CAB1374
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 606-745 of human Myeloperoxidase (MPO) (NP_000241.1).
Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils.
Purification Method:
Affinity purification
Gene ID:
4353
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Immunofluorescence analysis of rat bone marrow using Myeloperoxidase (MPO) Rabbit pAb (CAB1374) at dilution of 1:100 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
