The MPC2 Polyclonal Antibody (CAB20196) is a valuable tool for research focused on the mitochondrial pyruvate carrier 2 (MPC2) protein. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the MPC2 protein, this antibody enables the accurate detection and analysis of this critical mitochondrial transporter in various cell types.MPC2 is a key player in cellular metabolism, specifically in the transport of pyruvate into the mitochondria for energy production.
Dysregulation of MPC2 has been linked to metabolic diseases, cancer, and neurodegenerative disorders, making it a promising target for therapeutic interventions. Research into the function and regulation of MPC2 is essential for understanding its role in these diseases and for the development of potential treatments.
Product Name:
MPC2 Rabbit Polyclonal Antibody
SKU:
CAB20196
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-60 of human MPC2 (NP_056230.1).
inner mitochondrial membrane protein complex, mitochondrial inner membrane, mitochondrion, nucleus
Calculated MW:
14kDa
Observed MW:
14kDa
Enables identical protein binding activity. Predicted to be involved in mitochondrial pyruvate transmembrane transport. Predicted to act upstream of or within mitochondrial acetyl-CoA biosynthetic process from pyruvate and positive regulation of insulin secretion involved in cellular response to glucose stimulus. Located in mitochondrion.
Purification Method:
Affinity purification
Gene ID:
25874
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse kidney, using MPC2 Rabbit pAb (CAB20196) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
