The MPC1 Polyclonal Antibody (CAB20195) is a valuable tool for researchers studying MPC1, a key protein involved in mitochondrial pyruvate transport. This antibody, raised in rabbits, is highly specific to human samples and is validated for use in Western blot applications. By binding to the MPC1 protein, this antibody allows for the detection and analysis of MPC1 in various cell types, making it an essential reagent for studies in mitochondrial biology and metabolism.MPC1 plays a crucial role in the regulation of glucose metabolism and energy production in the mitochondria.
Dysregulation of MPC1 has been linked to various diseases, including metabolic disorders and cancer. Therefore, understanding the function and expression of MPC1 is essential for developing targeted therapies for these conditions.This MPC1 antibody is a reliable tool for researchers seeking to investigate the role of MPC1 in metabolic pathways and disease progression. Its high specificity and sensitivity make it an ideal choice for experimental studies in cell biology and biochemistry. Unlock the potential of MPC1 research with the CAB20195 antibody.
Product Name:
MPC1 Rabbit Polyclonal Antibody
SKU:
CAB20195
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-109 of human MPC1 (NP_057182.1).
WB,1:500 - 1:1000 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Synonyms:
MPYCD; BRP44L; CGI-129; SLC54A1; MPC1
Positive Sample:
HepG2,K-562,Mouse liver,Rat heart
Conjugate:
Unconjugated
Cellular Localization:
inner mitochondrial membrane protein complex, mitochondrial inner membrane, mitochondrion
Calculated MW:
12kDa
Observed MW:
12kDa
The protein encoded by this gene is part of an MPC1/MPC2 heterodimer that is responsible for transporting pyruvate into mitochondria. The encoded protein is found in the inner mitochondrial membrane. Defects in this gene are a cause of mitochondrial pyruvate carrier deficiency. Several transcript variants, some protein coding and one non-protein coding, have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
51660
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MPC1 Rabbit pAb (CAB20195) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
